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عمومی::
کار آزمایی کنترل شده تصادفی چندمرکزی
Six months later, Nielsen et al. published a large multicenter randomized controlled trial (mRCT) that did not find any difference in mortality in patients treated with mild hypothermia (33 °C) compared with normothermia (36 °C) [5].
In this chapter we report briefly the mRCT published from June 21, 2015, to January 31, 2015, focusing on interventions that showed a significant effect on mor- tality in adult critically ill patients.
Only four mRCTs that fulfill our inclusion criteria were found.
One large mRCT on the impact of colloids on survival in critically ill patients was published after the Consensus Conference [8].
Mentzelopoulos and colleagues designed a double-blinded mRCT to investi- gate the effect on survival with good neurological outcome (cerebral performance
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